Presentation summary

Background and objective :
Lung cancer patients often experience severe symptoms such as dyspnea and fatigue, which significantly reduce quality of life. Treatment options vary based on cancer type, stage, and patient condition, including surgery, radiotherapy, and systemic therapies. Cancer-related fatigue (CRF) and treatment burden may arisedirectly or indirectly from lung cancer therapies, particularly prominent in advanced-stage patients receiving combined therapies. The use of Korean medicine, such as herbal remedies and acupuncture, is increasing among cancer patients in Korea, and emerging evidence suggests potential benefits for symptom management and quality of life. This retrospective study aims to investigate the clinical characteristics, cancer-related fatigue, quality of life, and safety of integrative Korean and Western medicine in hospitalized lung cancer patients, and to identify predictors of response to integrative therapy.

Method :
From January, 2021 to December, 2023, a total of 41 hospitalized lung cancer patients were included in this retrospective analysis. Patient data were collected through electronic medical records, including overall survival (OS), demographic characteristics, adverse events, scores from the FACT-L (Functional Assessment ofCancer Therapy-Lung) for quality of life, the BFI-K (Brief Fatigue Inventory-Korean) for fatigue and blood test results for safety. Kaplan-Meier curves were used to compare the differences in survival time. A Cox regression analysis was performed to determine the hazard ratio of the risk of mortality.

Result :
Among 41 hospitalized lung cancer patients, all received at least two types of Korean medicine treatments, with 41.5% undergoing herbal medicine, acupuncture, and moxibustion concurrently. Saengmaeksan was themost commonly prescribed herbal formula (63.4%). At admission, the mean FACT-L score was 79.51,reflecting a lower quality of life compared to previous studies. By cancer stage, early-stage…